Andrew Bujalski is heading south. His first film, “Funny Ha Ha’’ (2002), was set in his hometown of Boston; 2005’s “Mutual Appreciation’’ started here but ended up down the highway in New York City. “Beeswax,’’ Bujalski’s latest slice of 20-something anomie, tumbles off the map into Austin, Texas. It’s his sharpest, most observant piece of work yet, though. Sometimes you have to leave home to find yourself.
The main characters are twin sisters, Jeannie and Lauren, played by Tilly and Maggie Hatcher. Biologically identical, they couldn’t be more different in temperament and circumstance. Jeannie manages a small clothing boutique that she co-owns with a troublesome business partner (Anne Dodge); Lauren doesn’t seem to do much of anything. Jeannie is always looking for the next problem to focus on; Lauren breezes through life, assuming other people will fix her problems. Jeannie’s in a wheelchair. Lauren’s not.