But not all studies have been so clear-cut. One 2007 review by the Cochrane Collaboration, a nonprofit, international organization that evaluates medical research, involved pooling data from 51 pain studies; it showed that listening to music can reduce the intensity of pain and the need for narcotic drugs, but cautioned that, overall, the benefit was small.
Music therapy may also improve mental state and functioning in people with schizophrenia, according to a 2007 Cochrane review. Premature infants who listen to lullabies learn to suck better and gain more weight than those who don't get music therapy. And Deforia Lane, director of music therapy at the University Hospitals Ireland Cancer Center in Cleveland, has found an improvement in immune response among hospitalized children who played, sang, and created music compared to children who did not get music therapy.