With Mets fans playfully chasing Yankees' rooters with brooms, the Yankees avoided a Subway Series sweep and stopped a three-game losing streak.
Alex Rodriguez hit his big league-leading 17th homer and Derek Jeter and Jorge Posada also connected.
David Wright homered for the third time in two days for the Mets, and Damion Easley hit two-out homer off Mariano Rivera in the ninth. Their four-game winning streak ended, the Mets head to Atlanta leading the NL East by 2 1/2 games.
Promoted from Triple A earlier in the day after Darrell Rasner broke a finger, Clippard became the seventh rookie pitcher to start for the Yankees this season.
The 22-year-old Clippard (1-0) was magnificent over six innings and allowed just three hits, including Wright's solo homer.
Tigers 6, Cardinals 3 -- Justin Verlander stayed unbeaten in May and Brandon Inge homered to help host Detroit sweep St. Louis in a World Series rematch.
Verlander (5-1) pitched eight strong innings to pick up his fourth victory in four May starts and hand the Cardinals their fifth straight defeat.
The righthander gave up two runs and five hits with three strikeouts in his longest start of the season.
Padres 2, Mariners 1 -- Justin Germano held host Seattle to an unearned run and six hits in six innings to lift San Diego.
Germano (2-0) outpitched Mariners ace Felix Hernandez (2-2), who was making his second start after spending nearly a month on the disabled list with a strained right elbow. Hernandez worked five innings, allowing eight hits and two runs. He walked three and struck out nine.
Nationals 4, Orioles 3 -- Nook Logan's two-run single off reliever Danys Baez with two outs in the eighth capped a comeback and helped host Washington beat Baltimore, which blew a chance for its first three-game road sweep since 2005.
Brewers 6, Twins 5 -- Geoff Jenkins hit his 200th career homer and had five RBIs, including the go-ahead run in the seventh to help host Milwaukee rally from a four-run deficit.
Phillies 5, Blue Jays 3 -- Adam Eaton (4-3) pitched four-hit ball over six-plus shutout innings, and Pat Burrell and Aaron Rowand homered to lead host Philadelphia.
