Their strengths melded perfectly, critic Leonard Maltin wrote in his book "Of Mice and Magic: A History of American Animated Cartoons." Mr. Barbera brought the comic gags and skilled drawing, while Hanna brought warmth and a keen sense of timing.
"This writing-directing team may hold a record for producing consistently superior cartoons using the same characters year after year -- without a break or change in routine," Maltin wrote.
"From the Stone Age to the Space Age and from primetime to Saturday mornings, syndication and cable, the characters he created with his late partner, William Hanna, are not only animated superstars, but also a very beloved part of American pop culture," Warner Bros. chairman and chief executive Barry Meyer said.
Hanna, who died in 2001, once said he was never a good artist but his partner could "capture mood and expression in a quick sketch better than anyone I've ever known."
The two first teamed cat and mouse in the short "Puss Gets the Boot." It earned an Academy Award nomination, and MGM let the pair keep experimenting until the full-fledged Tom and Jerry characters were born.
Jerry was borrowed for the mostly live-action musical "Anchors Aweigh," dancing with Gene Kelly in a scene that became a screen classic.
After MGM folded its animation department in the mid-1950s, Hanna and Barbera were forced to go into business for themselves. With television's sharply lower budgets, their new cartoons put more stress on verbal wit than the detailed -- and expensive -- action featured in theatrical cartoon.
Their "Flintstones" was the first animated series on prime-time television. Like "The Simpsons" three decades later, "The Flintstones" found success in prime-time by not limiting its reach to children. The program, a parody of "The Honeymooners," was among the 20 most popular shows on television during the 1960-61 season, and Fred's shout of "yabba dabba doo!" entered the language.
The Jetsons, which debuted in 1962, were the futuristic mirror image of the Flintstones.