Sampson's second score put the Demons ahead, 14-6, in the third quarter and Northwestern was able to hold on from there, conceding only one more score, on Corey Parks's 15-yard touchdown reception from Anthony Orio.
Orio was 5-of-12 passing for 61 yards. Anthony Riley rushed for 99 yards on 11 carries for the Huskies, with nearly half of those yards coming on a 48-yard gain.
Maine 25, Delaware 13 -- Montell Owens rushed for 92 yards and two touchdowns as the Black Bears rallied for two fourth-quarter scores to defeat the visiting Blue Hens.
Maine (3-5, 1-4 Atlantic 10) got a first-quarter touchdown when Ron Whitcomb connected with Kevin McMahan from 47 yards. On Maine's next possession, Owens capped a 14-play, 80-yard drive with a 1-yard touchdown run early in the second quarter, and the Bears held a 13-0 lead.
Delaware (4-4, 1-4) got on the board late in the first half after a 19-play, 55-yard drive that spanned more than 10 minutes. Omar Cuff scored from 1 yard.
The Blue Hens tied the game at 13 after a field goal in the third and another early in the fourth.
After a turnover, Maine marched 88 yards and took the lead for good when Whitcomb found McMahan again, this time from 6 yards. Owens added his second touchdown less than a minute later after Maine's defense forced a fumble.
Villanova 35, William & Mary 21 -- Frank Jankowski threw three touchdown passes as the host Wildcats built a 28-point lead en route to the upset of the ninth-ranked Tribe.
Jankowski threw scoring passes of 15 yards to J.J. Outlaw and 14 yards to Anton Ridley in the first half. He added a 23-yarder to John Dieser after the break.
Martin Gibson scored on a 30-yard run for the Wildcats and Rodney Badger capped the scoring with a 15-yard interception return for a touchdown for Villanova (4-4, 2-3).
William & Mary (5-3, 3-2) got a pair of touchdowns off interceptions in the fourth quarter. Trevor McLaurin scored on a 37-yard return and James Miller returned a pick 80 yards for a score.
Hofstra 38, Rhode Island 24 -- Anton Clarkson passed for 415 yards and ran for a touchdown as the Pride beat the Rams in South Kingstown, R.I.
Clarkson completed 29 of 36 passes for Hofstra (5-3, 3-2). Devale Ellis caught 11 passes for 138 yards and wideout Charles Sullivan added 116 yards on five receptions.
Joe Casey carried 28 times for 170 yards for URI (4-5, 2-4).
Richmond 18, James Madison 15 -- At Harrisonburg, Va., Tim Hightower ran for 119 yards and two touchdowns as the Spiders edged the 17th-ranked Dukes.
Hightower had touchdowns of 19 and 1 yards. Joseph Fore added field goals of 23 and 34 yards for Richmond (5-3, 5-1).
Justin Rascati threw two touchdown passes for James Madison (4-4, 2-3).